Research Technician and Laboratory Manager at University of Oxford

About the role

We are seeking to appoint a Research Technician and Laboratory Manager to join the lab of Prof Nick Lakin.  The research team investigates the molecular basis of DNA repair and how this contributes to maintenance of genome integrity. Our specific interests are in deciphering the role of poly-ADP-ribose polymerases (PARPs) in the detection and signalling of DNA damage and how this promotes DNA repair. We have significant expertise in studying these processes in human cells and model organisms.

The Research Technician will manage our eukaryotic cell culture library and other lab stocks in addition to providing experimental support to a variety of projects. Tasks will involve cell-based assays for DNA repair, using genome editing technologies to generate cell lines and recombinant DNA technology.  The Research Technician will also act as laboratory manager for the research group, proactively maintaining stocks, equipment and facilities, health and safety protocols, and creating an effective working environment.

This full-time fixed-term post is funded by the Medical Research Council up to 6th June 2025 in the first instance. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

About you

You will hold a BSc Degree in an area of molecular and cell biology, genetics or biochemistry. You should have experience of mammalian cell culture, including clonal cell line generation and recombinant protein expression using mammalian expression systems. You will also have experience of employing cell-based assays to assess mechanisms of cell function. Experience in manipulating gene expression by siRNA and/or genome editing is also desirable.  You will have experience of working in laboratory environment and be able to work effectively with other lab members as part of a team.  Good organisational and management skills are expected in order to manage facilities and equipment effectively, together with being proactive and capable of taking the lead in maintaining an effective and orderly lab environment.

Application Process

You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application.

Only applications received before 12 noon on Friday 2nd February 2024 can be considered.  Interviews for shortlisted candidates will be held as soon as possible thereafter.

Committed to equality and valuing diversity